Image 1 of 1
Image 1 of 1
Image 1 of 1
Image 1 of 1
NAD (nicotinamide adenine dinucleotide) therapy is increasingly discussed for its roles in cellular energy, DNA repair, and metabolic health. Below is a clear, clinical overview comparing in-clinic NAD administration with at-home injection use, including benefits, risks, protocols, and practical considerations to help patients and providers make informed decisions.
What is NAD?
NAD is a coenzyme found in every cell that cycles between NAD+ and NADH forms, central to mitochondrial function, redox reactions, and as a substrate for enzymes involved in DNA repair and epigenetic regulation.
Interest in supplementation or replacement therapy focuses on boosting NAD+ levels to support energy metabolism, cognitive function, recovery from substance use disorders, age-related decline, and overall cellular resilience.
Forms of NAD therapy
Intravenous (IV) NAD: Direct infusion of NAD+ solution into a vein, typically performed in a medical setting.
Intramuscular (IM) or subcutaneous (SC) injections: Smaller-volume injections that can be given in clinic or, in some protocols, at home after training.
Oral NAD precursors (e.g., nicotinamide riboside, nicotinamide mononucleotide): Available OTC and by prescription; raise NAD+ indirectly and are less invasive.
In-clinic NAD administration Advantages
Medical supervision: Continuous monitoring for adverse reactions (allergic response, hypotension, nausea, flushing, arrhythmias).
Professional dosing and titration: Providers can tailor infusion rate and dose based on tolerance, goals, comorbidities, and concurrent medications.
Sterile environment and trained personnel reduce infection and administration errors.
NAD (nicotinamide adenine dinucleotide) therapy is increasingly discussed for its roles in cellular energy, DNA repair, and metabolic health. Below is a clear, clinical overview comparing in-clinic NAD administration with at-home injection use, including benefits, risks, protocols, and practical considerations to help patients and providers make informed decisions.
What is NAD?
NAD is a coenzyme found in every cell that cycles between NAD+ and NADH forms, central to mitochondrial function, redox reactions, and as a substrate for enzymes involved in DNA repair and epigenetic regulation.
Interest in supplementation or replacement therapy focuses on boosting NAD+ levels to support energy metabolism, cognitive function, recovery from substance use disorders, age-related decline, and overall cellular resilience.
Forms of NAD therapy
Intravenous (IV) NAD: Direct infusion of NAD+ solution into a vein, typically performed in a medical setting.
Intramuscular (IM) or subcutaneous (SC) injections: Smaller-volume injections that can be given in clinic or, in some protocols, at home after training.
Oral NAD precursors (e.g., nicotinamide riboside, nicotinamide mononucleotide): Available OTC and by prescription; raise NAD+ indirectly and are less invasive.
In-clinic NAD administration Advantages
Medical supervision: Continuous monitoring for adverse reactions (allergic response, hypotension, nausea, flushing, arrhythmias).
Professional dosing and titration: Providers can tailor infusion rate and dose based on tolerance, goals, comorbidities, and concurrent medications.
Sterile environment and trained personnel reduce infection and administration errors.