Migraine IV cocktail

$325.00

Migraine IV Cocktail (Myers-style) — Suggested Protocol

Indication

Migraine IV Cocktail (Myers-style) — Suggested Protocol

Indication

Acute migraine with moderate to severe pain, nausea, or significant functional impairment.

IV Medications and Dosages

Toradol (ketorolac): 30 mg IV push — single dose for acute analgesia (avoid if contraindications such as active bleeding, renal impairment, or recent NSAID use).
Zofran (ondansetron): 4 mg IV push — antiemetic to address nausea and reduce vomiting-associated triggers.
Benadryl (diphenhydramine): 50 mg IV or IM — for antiemetic/sedation and to mitigate potential histamine-mediated symptoms; use caution with sedation and in elderly patients.
Magnesium sulfate: 800 mg IV (0.8 g) administered over 15–30 minutes — for acute migraine relief and potential prophylactic benefit; consider slower infusion in patients with renal impairment or cardiac conduction disease.
Optional additions commonly included in a Myers-style cocktail: B-complex vitamins (e.g., B12 1,000 mcg IM or IV), vitamin C 500–1,000 mg IV, and normal saline or lactated Ringer’s as the infusion carrier (total volume individualized, often 100–250 mL).

Administration Notes

Assess vital signs, allergies, medication history, renal function, pregnancy status, and concurrent anticoagulant or NSAID use prior to administration.
Use an IV line suitable for medication administration; dilute medications per manufacturer recommendations when required.
Administer Toradol only if no contraindications (age >65 caution, renal impairment, active bleeding, recent major surgery).
Monitor for sedation, respiratory depression (especially if additional sedatives are used), hypotension, and signs of allergic reaction during and after infusion.
Monitor urine output and consider baseline serum magnesium if concern for renal dysfunction.

Contraindications and Precautions

Quantity:

Migraine IV Cocktail (Myers-style) — Suggested Protocol

Indication

Migraine IV Cocktail (Myers-style) — Suggested Protocol

Indication

Acute migraine with moderate to severe pain, nausea, or significant functional impairment.

IV Medications and Dosages

Toradol (ketorolac): 30 mg IV push — single dose for acute analgesia (avoid if contraindications such as active bleeding, renal impairment, or recent NSAID use).
Zofran (ondansetron): 4 mg IV push — antiemetic to address nausea and reduce vomiting-associated triggers.
Benadryl (diphenhydramine): 50 mg IV or IM — for antiemetic/sedation and to mitigate potential histamine-mediated symptoms; use caution with sedation and in elderly patients.
Magnesium sulfate: 800 mg IV (0.8 g) administered over 15–30 minutes — for acute migraine relief and potential prophylactic benefit; consider slower infusion in patients with renal impairment or cardiac conduction disease.
Optional additions commonly included in a Myers-style cocktail: B-complex vitamins (e.g., B12 1,000 mcg IM or IV), vitamin C 500–1,000 mg IV, and normal saline or lactated Ringer’s as the infusion carrier (total volume individualized, often 100–250 mL).

Administration Notes

Assess vital signs, allergies, medication history, renal function, pregnancy status, and concurrent anticoagulant or NSAID use prior to administration.
Use an IV line suitable for medication administration; dilute medications per manufacturer recommendations when required.
Administer Toradol only if no contraindications (age >65 caution, renal impairment, active bleeding, recent major surgery).
Monitor for sedation, respiratory depression (especially if additional sedatives are used), hypotension, and signs of allergic reaction during and after infusion.
Monitor urine output and consider baseline serum magnesium if concern for renal dysfunction.

Contraindications and Precautions